I think what God wants from us in our personal lives is to listen to what He has said in His Word. There is instruction for us for every situation in our lives. Of course not every single scenario in our lives is touched upon in the bible, because we would need a truck to carry it, and so that’s where His principles come in. Unfortunately, because the bible doesn’t mention something specifically, some people use that opportunity to indulge in it. Ex: the bible doesn’t mention Halloween but it does talk about not celebrating pagan festivals. Some would say that it’s not written, or that we have Christian liberty, or that it’s a gray area etc. Pick any excuse. But the truth of the matter is, it IS written, and it would be easily seen and recognized if we weren’t looking for loopholes in order to indulge in our favorite sin.
Back to the original question. As far as finding comfort in what God wants for us….some people might have questions about what decision to make about a job and who to marry etc. but this is where the Christian liberty comes in. What He requires of us is to obey Him, not go buy a particular car or take a particular job. We are not disobeying Him or getting out of His will if we make a decision about a car or spouse. We just have to make them with Godly principles in mind. (are we being good stewards with our money – are we equally yoked) We are looking for answers to questions that have already been answered for us. And if we do make an unwise decision, we will learn from it and benefit from it. There is Godly instruction or a biblical principle behind every situation and/or decision we are in/make. There is no need to ask the Lord about these little particulars because we already know what is required of us.
So how am I comforted in knowing what God wants for my life? I make sure that I do what’s in His Word i.e. obey Him.